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2019, 02, v.35;No.200 179-184
石菖蒲药效物质基础和作用机制研究进展
基金项目(Foundation): 国家自然科学基金项目(81273629、81473375、81530099);; 山西省回国留学人员科研项目(2013-134);; 山西省留学回国人员科技活动择优资助项目;; 山西省高等学校创新人才支持计划;; 中国博士后科学基金一等资助项目(2013M540066)
邮箱(Email): hewenbinbin@aliyun.com;
DOI: 10.13412/j.cnki.zyyl.2019.02.041
发布时间: 2019-04-15
出版时间: 2019-04-15
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摘要:

石菖蒲为常用芳香开窍中药,主要含有挥发油类、黄酮类、醌类、生物碱类、三萜皂苷类、苯丙素类、有机酸类、氨基酸类及糖类等化学成分,具有镇静、抗抑郁、抗痴呆、保护心肌细胞、健胃、抗氧化、镇咳平喘、抑菌抗炎、抗疲劳等多种药理作用,常作为主要组成药物出现于治疗中枢神经系统疾病的古代经典名方中,在心血管系统、呼吸系统及消化系统也具有良好的药理学活性。现对近年来石菖蒲药效物质基础和作用机制的研究进展进行综述。

Abstract:

Acorus tatarinowii Schott is common used as Fangxiangkaiqiao Chinese medicine, mainly containing volatile oils, flavonoids, anthraquinones, alkaloids, triterpenoid saponins, phenylpropanoids, organic acids, amino acids and glucose. It has pharmacological effect of sedative, anti-depressive, anti-dementia, cardiomyocytes protection, stomachic, anti-oxidation, relieving cough and asthma, anti-inflammatory and anti-fatigue, etc. It often appears as the main constituent drug in the classic traditional Chinese prescription for the treatment of central nervous system diseases. It also shows the good pharmacological activity in the cardiovascular system, respiratory system and digestive system. In this assay, we mainly review the research progress of the material basis and mechanism of Acorus tatarinowii Schott.

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基本信息:

DOI:10.13412/j.cnki.zyyl.2019.02.041

中图分类号:R285

引用信息:

[1]郭美彤,赵佳奇,韩诚,等.石菖蒲药效物质基础和作用机制研究进展[J].中药药理与临床,2019,35(02):179-184.DOI:10.13412/j.cnki.zyyl.2019.02.041.

基金信息:

国家自然科学基金项目(81273629、81473375、81530099);; 山西省回国留学人员科研项目(2013-134);; 山西省留学回国人员科技活动择优资助项目;; 山西省高等学校创新人才支持计划;; 中国博士后科学基金一等资助项目(2013M540066)

发布时间:

2019-04-15

出版时间:

2019-04-15

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